Long-Term Outcomes in the Management of Painful Diabetic Neuropathy

Pregabalin versus Gabapentin in the Management of Painful Diabetic Neuropathy

Diabetic neuropathy develops in the majority of poorly controlled diabetic patients as a late complication. Painful diabetic neuropathy represents a major health problem as it may present with excruciating neuropathic pain and is responsible for substantial morbidity, increased mortality and impaired quality of life. The aim is to compare the efficacy of Pregabalin and Gabapentin in painful dia...

Painful Diabetic Neuropathy

N europathic pain exerts a substantial impact on quality of life, particularly by causing considerable interference in sleep, daily activities, and enjoyment of life. Chronic neuropathic pain is present in 13–26% of diabetic patients (1– 4). In a recent survey from Augsburg, Germany, the prevalence of painful polyneuropathy was found to be 13.3% in diabetic subjects, 8.7% in individuals with im...

Painful diabetic neuropathy.

PDN is commonly caused by involvement of either the C fibres or the Aδ fibres. PDN caused by the involvement of small nerve fibers (C fibres), may present without objective clinical findings, such as decreased peripheral reflexes or abnormalities, on routine electrophysiological studies. Small fiber neuropathies may manifest as a number of different clinical symptoms, including allodynia, burni...

Painful diabetic neuropathy pdf

Recent Advances in Management of Painful Diabetic Neuropathy

Painful diabetic neuropathy are common and present a major challenge to the practicing physician. Pain is universal symptom in patients with rare acute sensory neuropathy and is present in only upto 50% of those patients with the common chronic sensory motor neuropathy. The first step in symptom management is to stabilize glycemic control. There is increasing evidence that blood glucose flux ma...